Learning About Fibroids and Anemia Related to Fibroids
If you have uterine fibroids, you are
not alone. An estimated one in four
women of childbearing age have fibroids.1 The good news
is that fibroids can be treated.
Do not take Lupron Depot if you are or may become pregnant, are breast-feeding, have
undiagnosed vaginal bleeding, or if you have experienced any type of allergic reaction to
Please see Important Safety Information you should know about Lupron Depot and discuss it with your doctor.
Please see the full Prescribing Information for Lupron Depot.
What are fibroids?
Uterine fibroids are growths, or tumors, that develop in the muscular wall of the uterus. They may also be called myomas, leiomyomas, leiomyomata uteri, or simply fibroids. Fibroids are generally benign—that is, they are not cancerous (malignant). A woman may have just one fibroid, or many. Fibroids are the most common kind of growths associated with the uterus. It is estimated that as many as 3 out of 4 women will have uterine fibroids at some point during their lives, but most are unaware of them because they often cause no symptoms. Only about one-third of these fibroids are large enough to be detected by a physician during a physical examination, and many do not require treatment.2
Uterine fibroids can range in size, for example,
from as small as a grape (less than
They can appear:
- Beneath the outer surface of the uterus
- Totally within the wall of the uterus
- Inside the uterus
What causes fibroids?
Not much is known about the cause of fibroids. But evidence suggests that their growth is related to estrogen and other hormones. In fact, increased levels of these hormones may speed up the growth rate of the fibroids.
Factors that may play a role in a woman’s risk of developing fibroids include:
|Age:||Women between the ages of 30 and 45 are commonly diagnosed with fibroids1|
|Weight:||Overweight women are at a higher risk to develop fibroids4|
African-American women tend to
have the highest risk of developing
although fibroids have been found in women of all ethnic backgrounds2
What are some common symptoms and possible complications of fibroids?
- Heavy or prolonged menstrual bleeding
- Bleeding between periods
- Pain or feeling of pressure in the lower abdomen
- Excessive bleeding due to fibroids may lead to anemia
Anemia related to fibroids
Uterine fibroids often cause heavy and prolonged menstrual bleeding which can cause a type of anemia.
Some signs and symptoms of this type of anemia include:
- Paler skin than usual
- Feeling tired or weak
- Feeling cold or hot from exertion
- A sore or swollen tongue
- Cracks in the sides of the mouth
If you have any of these signs or symptoms, talk to your doctor.
Use and Important Safety Information You Should Know About
Lupron Depot® (leuprolide acetate for depot suspension)
LUPRON DEPOT® (leuprolide acetate for depot suspension) 3.75 mg for 1-month and 11.25 mg for 3-month administration with iron therapy are used before fibroid surgery to improve anemia due to vaginal bleeding from fibroids. Your doctor may consider a
Important Safety Information
Do not take LUPRON DEPOT if you are or may become pregnant, are breast-feeding, have undiagnosed vaginal bleeding, or if you have experienced any type of allergic reaction to
Thinning of the bones may occur during therapy with LUPRON DEPOT, which may not be completely reversible in some patients. Since some conditions may increase the possibility of bone thinning, you should tell your doctor if you smoke, use alcohol in excess, have a family history of osteoporosis (thinning of the bones with fractures), or are taking other medications that can cause thinning of the bones.
After beginning LUPRON DEPOT, your estrogen levels will increase for
LUPRON DEPOT is not a method of birth control. Even though you may not have periods, unprotected intercourse could result in pregnancy. You should use non-hormonal birth control such as condoms, a diaphragm with contraceptive jelly, or a copper IUD to prevent pregnancy. If you think you have become pregnant while on
There is a possibility of the development or worsening of depression and/or the occurrence of forgetfulness. Patients who have a history of depression should be carefully observed during treatment.
Convulsions have been observed in patients taking leuprolide acetate.
The most common side effects of LUPRON DEPOT include hot flashes, vaginal dryness, headaches, changes in mood, decreased interest in sex, depression, and/or the occurrence of forgetfulness.
LUPRON DEPOT must be administered in your doctor’s office.
For more information, talk with your health care provider.